医学期刊论文翻译ChineseMedi

CD4+cellsasapotentialbiomarkerforcytomegalovirusretinitisinchildrenwithacutelymphocyticleukemia在儿童急性淋巴细胞白血病中CD4+细胞可作为巨细胞病毒性视网膜炎一个潜在的生物标记TotheEditor:Infectionisoneofthecausesofdeathafterchemotherapyinchildrenwithleukemia.About20%to30%acutelymphocyticleukemia(ALL)patientsdiefrominfectionafterchemotherapy.Patientswithimmunedeficiency,underchemotherapy,ortreatedwithimmunosuppressoraremoreinclinedtobeinfectedwithhumancytomegalovirus(HCMV)whichleadstoseveresystematicdisorders.Cytomegalvirusretinitis(CMVR)isamajorsightthreateningdiseasewhichmainlyoccursinpatientswithimmunedeficiencyandresultsinblindnessiftreatmentisdelayed.ThedecreaseofCD4+TcellshasbeenrelatedtoCMVRinimmunedeficiencysyndromelikeAIDS.However,littleisknownabouttherelationbetweenthelevelofTcellswithdifferentmarkersandtheonsetofCMVRinALLpatientsunderchemotherapy.Therefore,thisstudywasdesignedtoinvestigatethediagnosticvalueofTcellswithdifferentmarkersforcytomegalovirusretinitisafterchemotherapyinpatientswithALL.致编辑：儿童白血病化疗后受到的感染是致死原因之一。大约20％到30％的急性淋巴细胞白血病（简称：急淋）患者死于化疗后的感染。有免疫缺陷，接受化疗或者免疫抑制剂治疗的患者更容易感染人巨细胞病毒，导致严重的系统性疾病。巨细胞病毒性视网膜炎主要是视力受损的疾病，主要发生在免疫缺陷的患者，如果延迟治疗，会导致失明。CD4+T细胞的减少和巨细胞病毒性视网膜炎在免疫缺陷综合征上相关，如艾滋病。然而，很少人知道急淋患者化疗后巨细胞病毒性视网膜炎的发生与T细胞的水平是否相关，T细胞可以使用不同的标记物显示。因此，（实验者）设计该研究去探讨使用不同标记的T细胞对急淋患者化疗后患巨细胞病毒性视网膜炎的诊断价值。Onehundredtwenty-eightchildrenwithALLwhowereunderchemotherapyinthedepartmentofhematologyfromourhospitaIfromJanuarytoSeptemberwereincludedinthisstudy.Inclusioncriteria:(1)ALLwasdiagnosedbybonemarrowexamination;(2)ALLpatientswereundermoderateriskandunderuniformchemotherapyregimens;(3)Medicalrecordwas







































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